| Spoiler warning: The following contains plot details about|
the entire movie.
Framed by a tour group visiting a statue of Ben Franklin, the story reveals the contributions of a mouse, Amos, to Franklin's career. Narrated by Amos, through his memoirs, the mouse recalls how he first met and befriended Benjamin Franklin, eventually aiding in his publishing, inventions, and political career. Amongst Amos' contributions were bifocals, inspiring Franklin to build the stove, and changing the format of Poor Richard's Almanac to an event-oriented newspaper. After Ben's experiments with electricity endanger Amos' life, Amos and Franklin part ways, finally reuniting in the midst of the American Revolution, and assisting Thomas Jefferson with the invention of the Declaration of Independence.
Spoilers end here.